Wednesday, October 7 |
Joint CPTC/IMAT Session |
7:30 a.m. - 8:00 a.m. |
Registration and Morning Break |
8:00 a.m. - 8:05 a.m. |
Welcome and Introduction
Mark Lim, Ph.D.
Innovative Molecular Analysis Technologies (IMAT)
National Cancer Institute, National Institutes of Health
Henry Rodriguez, Ph.D., M.B.A.
Director, Clinical Proteomic Technologies for Cancer
National Cancer Institute, National Institutes of Health
|
8:05 a.m. - 8:45 a.m. |
Keynote Lecture:
Elucidation of Tumor Biology and Assessment of Cancer Patients using Quantitative Mass Spectrometry
John Koomen, Ph.D.
Scientific Director, Proteomics Core Facility
H. Lee Moffitt Cancer Center and Research Institute |
8:45 a.m. - 11:30 a.m. |
CPTC and IMAT Joint Theme Session:
Immunoaffinity Platforms and Protein Arrays
Co-Chairs: CPTC Representative (Susan Fisher, Ph.D.)
IMAT Representative (Mark Limm, Ph.D.) |
8:45 a.m. - 9:10 a.m. |
High-Speed Label-Free Detection by Spinning-Disk Micro-Interferometry
Fred Regnier, Ph.D.
Purdue University |
9:10 a.m. - 9:35 a.m. |
The Prevalence and Nature of Glycan Alterations on Specific Proteins in Pancreatic Cancer Patients Revealed Using Antibody-Lectin Sandwich Arrays
Brian Haab, Ph.D.
Van Andel Research Institute |
9:35 a.m. - 10:00 a.m. |
Clinically Quantifying Low-abundance Serum Proteins by LC-
MS/MS: Potential Benefits and a Case Study
Andy Hoofnagle, M.D., Ph.D.
University of Washington |
10:00 a.m. - 10:15 a.m. |
Break |
10:15 a.m. - 10:40 a.m. |
Bead Array-mass Spectrometer: Equipment and Method Development
Scott Tanner, Ph.D.
University of Toronto |
10:40 a.m. - 11:05 a.m. |
Multiplex Mass Spectrometric Immunoassays
Dobrin Nedelkov, Ph.D.
Intrinsic Bioprobes (SBIR) |
11:05 a.m. - 11:30 a.m. |
FDA Regulation of Protein-Based Diagnostic Assays
Jeffrey N. Gibbs, J.D.
Hyman, Phelps and McNamara, P.C. |
11:30 a.m. - 11:45 a.m. |
Diversity Training Opportunities
Mark Lim, Ph.D. (introduction)
Innovative Molecular Analysis Technologies
National Cancer Institute, National Institutes of Health
Kristina Pohaku Mitchell (M.S., Ph.D. candidate)
University of California, San Diego |
11:45 a.m. - 1:00 p.m. |
Lunch and Poster Session (CPTC Sessions Ends) |
Afternoon Session: IMAT Session Begins |
1:30 p.m. – 1:45 p.m. |
Welcome and program update
Mark D. Lim, Ph.D.
Innovative Molecular Analysis Technologies (IMAT)
National Cancer Institute, National Institutes of Health |
1:45 p.m. – 2:45 p.m. |
Mini-med school: Clinical technologies and the need for innovation
Carolyn Compton, M.D., Ph.D.
Office of Biorepositories and Biospecimen Research
National Cancer Institute |
2:45 p.m. – 3:15 p.m. |
Patient Advocate |
3:15 p.m. – 3:45 p.m. |
Challenges in the “-omics” and Resources at NIST for Developing
Innovative Technologies
Michael D. Amos, Ph.D.
Biosciences Advisor, Director’s Office
Chemical Science and Technology Laboratory
National Institute of Standards and Technology |
3:45 p.m. – 4:15 p.m. |
Coffee break |
4:15 p.m. - 6:45 p.m. |
Technologies for Proteomics |
4:15 p.m. – 4:35 p.m. |
Architectural Proteomics for Early Risk Assessment in Breast Cancer
David Knowles, Ph.D.
Lawrence Berkeley National Laboratory |
4:35p.m. – 4:40 p.m. |
Questions and Answers |
4:40 p.m. – 5:00 p.m. |
Capillary Electrophoresis for Analysis of Barrett's Esophagus Biopsies
Lauren Ramsay, Ph.D.
University of Washington |
5:00 p.m. – 5:05 p.m. |
Questions and Answers |
5:05 p.m. – 5:25 p.m. |
Mesoporous Metal Oxide Nanomaterials for Mass Spectrometry-based Phosphoproteomics for the Molecular Analysis of Cancers
Jin Song, Ph.D.
University of Wisconsin-Madison |
5:25 p.m. – 5:30 p.m. |
Questions and Answers |
5:30 p.m. – 5:50 p.m. |
Microdialysis Combined with Proteomics for Protein Identification in Breast Tumor Microenvironment in vivo
Baogang J. Xu, Ph.D.
Vanderbilt University Medical Center |
5:50 p.m. – 5:55 p.m. |
Questions and Answers |
5:55 p.m. - 6:15 p.m. |
OxMRM: Quantifying Oxidation of Endogenous Redox-Sensitive Cysteines Using Multiple Reaction Monitoring
Jason Held, Ph.D.
Buck Institute for Age Research |
6:15 p.m. – 6:20 p.m. |
Questions and Answers |
6:20 p.m. - 6:40 p.m. |
Smart Nanoparticles Overcome Basic Roadblocks to Biomarker Discovery and Validation
Lance Liotta, Ph.D.
George Mason University |
6:40 p.m. – 6:45 p.m. |
Questions and Answers |
Thursday, October 8 |
8:30 a.m. – 9:30 a.m. |
The Need for Technologies in the Biospecimen Sciences
Carolyn Compton, M.D., Ph.D.
Office of Biorepositories and Biospecimen Research
National Cancer Institute |
9:30 a.m. – 10:00 a.m. |
An Innovative Biospecimen Science Technology
Michael Tangrea, Ph.D.
National Cancer Institute |
10:00 a.m. – 11:10 a.m. |
Technologies for Genomics and Epigenomics |
10:00 a.m. – 10:20 a.m. |
Abscription-Based Bisulfite-Free CpG Island Detection
Michelle Hanna, Ph.D.
Ribomed Biotechnologies |
10:20 a.m. – 10.25 a.m. |
Questions and Answers |
10:25 a.m. – 10:45 a.m. |
Development of Dynamic Single Molecule Analysis Platform using Nanochannel Array
Han Cao, Ph.D.
BioNanomatrix |
10:45 a.m. – 10:50 a.m. |
Questions and Answers |
10:50 a.m. – 11:10 a.m. |
Genome Sequencing Technology for Studying Melanoma
Jeremy Edwards, Ph.D.
University of New Mexico Health Sciences Center |
11:10 a.m. – 11:15 a.m. |
Questions and Answers |
11:15 a.m. – 11:35 a.m. |
Replacing PCR with COLD-PCR technology enriches variant DNA sequences and redefines the sensitivity of mutational profiling in cancer
G. Mike Makrigiorgos, Ph.D.
Dana Farber Cancer Institute |
11:35 a.m. – 11:40 a.m. |
Questions and Answers |
11:40 a.m. – 12:10 p.m. |
Keynote Speaker |
12:10 p.m. – 1:30 p.m. |
Lunch and Meet the Experts |
1:30 p.m. - 3:30 p.m. |
Imaging, Microfluidics and Nanotechnologies |
1:30 p.m. – 1:50 p.m. |
Application of a Novel Nanotechnology for Molecular Profiling of Tumor Cellular Elements
Edward L. Nelson, M.D.
University of California at Irvine |
1:50 p.m. – 1:55 p.m. |
Questions and Answers |
1:55 p.m. – 2:15 p.m. |
Partial-Wave Spectroscopic Microscopy for Surveillance and Diagnosis of Gastrointestinal Malignancies
Yang Liu, M.D., Ph.D.
University of Pittsburgh |
2:15 p.m. – 2:20 p.m. |
Questions and Answers |
2:20 p.m. – 2:40 p.m. |
High throughput high-content cell screening in a microfluidic device
Andre Levchenko, Ph.D.
Johns Hopkins University |
2:40 p.m. – 2:45 p.m. |
Questions and Answers |
2:45 p.m. – 3:00 p.m. |
Microfluidic Devices for Analysis of Circulating Tumor Cells
John Zhong, Ph.D.
University of Southern California |
3:00 p.m. – 3:05 p.m. |
Questions and Answers |
3:05 p.m. – 3:25 p.m. |
Using New Optical Techniques to Study Cell Signaling in 3D Matrices
Patricia J. Keely, Ph.D.
University of Wisconsin-Madison |
3:25 p.m. – 3:30 p.m. |
Questions and Answers |
3:30 p.m. – 4:00 p.m. |
Coffee break |
4:00 p.m. – 5:40 p.m. |
Technologies for Drug Discovery and Delivery |
4:00 p.m. - 4:20 p.m. |
Fluorescent Tracking of DNA Damage and Repair in Living Cells and Tumors: A Novel Tool for Cancer Biology and Drug Discovery
Stephen Kron, M.D., Ph.D.
University of Chicago |
4:20 p.m. – 4:25 p.m. |
Questions and Answers |
4:25 p.m. - 4:45 p.m. |
Targeting Vascular Endothelial Caveolae to Pump Antibodies into Tumors for Enhanced Specific Imaging and Therapy
Jan Schnitzer, M.D.
PRISM |
4:45 p.m. – 4:50 p.m. |
Questions and Answers |
4:50 p.m. – 5:10 p.m. |
Targeted Delivery of Folate-Conjugated Polymer/siRNA Complexes to Cancer Cells and Subsequent Gene Down-Regulation
Yilin Zhang, Ph.D.
University of Southern Mississippi |
5:10 p.m. – 5:15 p.m. |
Questions and Answers |
5:15 p.m. – 5:35 p.m. |
Using Synthetic Dosage Lethality to Find Novel Anti-Cancer Targets
Rodney Rothstein, Ph.D.
Columbia University Medical Center |
5:35 p.m. – 5:40 p.m. |
Questions and Answers |
Friday, October 9 |
8:30 a.m. – 9:10 a.m. |
Keynote |
9:00 a.m. – 9:10 a.m. |
Questions and Answers |
9:10 a.m. – 11:10 a.m. |
IMAT Session: Federal Guidance |
11:10 a.m. – 11:30 a.m. |
Break |
11:30 a.m. – 12:00 p.m. |
Closing Keynote Speaker |
12:00 p.m.– 12:10 p.m. |
Questions and Answers |
