2013 Annual Principal Investigators Meeting - NCI Alliance for Nanotechnology in Cancer - September 17-19, 2013 - Bethesda, MD
 

Draft Agenda

Nano PI Meeting (Bethesda)—September 17-19, 2013

NCL Lessons Learned Workshop (Rockville)—September 20, 2013

**NOTE: presentation titles are subject to change

Tuesday, September 17, 2013

7:30 a.m. - 8:30 a.m. Registration and Poster Setup
8:30 a.m. - 9:00 a.m. Welcome and Introduction
Piotr Grodzinski
National Cancer Institute, NIH

Doug Lowy
National Cancer Institute, NIH

Peter Searson
Johns Hopkins Center of Cancer Nanotechnology Excellence

Session I Challenges and Opportunities for Nanotechnology in Cancer (9:00 a.m. - 11:20 a.m.)
Chair: Joel Tepper, University of North Carolina at Chapel Hill
9:00 a.m. - 9:30 a.m. Nano-devices for In-vitro Diagnosis and Therapy Monitoring – What do We Measure and How Sensitive Does the Measurement Need to Be?
Ralph Weissleder
Harvard University
Center of Cancer Nanotechnology Excellence
9:30 a.m. - 10:10 a.m. Collection and Analysis of “Omic” Data to Provide Accurate Diagnosis and Treatment
Anil Sood and Wei Zhang
The University of Texas MD Anderson Cancer Center
Center of Cancer Nanotechnology Excellence
10:10 a.m. - 10:50 a.m. Predicting Targeted Therapy Combinations for GBM
James Heath and Tim Cloughesy
California Institute of Technology and UC Los Angeles
Center of Cancer Nanotechnology Excellence
10:50 a.m. - 11:20 a.m. Reformulation of Failed Drugs Using Nanoparticle Strategies
Andrew Wang
The University of North Carolina at Chapel Hill
Center of Cancer Nanotechnology Excellence
11:20 a.m. - 1:00 p.m. Lunch (on your own)
11:30 a.m.-1:00 p.m. CGC Working Lunch (by invitation only)
Session II (1:00 p.m. - 3:00 p.m.)
Chair: Peter Searson Johns Hopkins University
1:30 p.m. - 2:00 p.m. Targeted Tumor-Penetrating siRNA Nanocompanies for Cancer Therapy
Sangeeta Bhatia
Massachusetts Institute of Technology
Center of Cancer Nanotechnology Excellence

1:30 p.m. - 2:00 p.m. Preclinical Proof of Concept Evaluation of a Nanomedicine Candidate Targeting Blood Cancers
Fatih Uckun
University of Southern California
Cancer Nanotechnology Platform Partnerships

2:00 p.m. - 2:30 p.m. Digital Breast Tomosynthesis and Microbeam Radiation Therapy Using CNT X-Ray Technology
Otto Zhou
The University of North Carolina at Chapel Hill
Center of Cancer Nanotechnology Excellence
2:30 p.m. - 3:00 p.m. Mucus Penetrating Nanoparticles for Small-Cell Lung Cancer
Justin Hanes
Johns Hopkins University
Center of Cancer Nanotechnology Excellence
3:00 p.m. - 3:30 p.m. Break

Session III-A (Parallel Sessions, 3:30 p.m. - 5:30 p.m.)
Chair: Julia Y. Ljubimova, Cedars–Sinai Medical Center

3:30 p.m. - 3:50 p.m. In Vivo Quantification of Cancer Vaccine-Mediated Antigen Delivery to Lymph Nodes Using MRI
Jeff Bulte
Johns Hopkins University
Center of Cancer Nanotechnology Excellence
3:50 p.m. - 4:10 p.m. Combinatorially-Designed Nano-Platforms: opportunity for Targeted Delivery of Drugs and siRNA
Mansoor Amiji
Northeastern University
Cancer Nanotechnology Platform Partnerships
4:10 p.m. - 4:30 p.m. Magnetoresistive Sensor Platform for Parallel Cancer Marker Detection
Marc Porter
University of Utah
Cancer Nanotechnology Platform Partnerships
4:30 p.m. - 4:50 p.m. Nanoparticle Drug Delivery Systems Design at the University of Kentucky Cancer Nanotechnology Training Center (UK CNTC)
Bradley Anderson
University of Kentucky, Lexington
Cancer Nanotechnology Training Center
4:50 p.m. - 5:10 p.m. Effective Gold Nanorod (AuNRs) Sizes and Their Application for Plasmonic Photothermal Therapy (PPTT) in SCCHN Xenograft Model
Dong Moon Shin
Emory University
Cancer Nanotechnology Platform Partnerships
5:10 p.m. - 5:30 p.m. Tumor Targeted Nanobins for the Treatment of Metastatic Breast and Ovarian Cancers
Thomas O’Halloran
Northwestern University
Cancer Nanotechnology Platform Partnerships

Session III-B (Parallel Sessions, 3:30 p.m. - 5:30 p.m.)
Chair: Rashid Bashir, University of Illinois at Urbana–Champaign

3:30 p.m. - 3:50 p.m. Magneto-Nano Chips for Ultrasensitive and Multiplex Detection of Protein Biomarkers of Tumor
Shan Wang
Stanford University
Center of Cancer Nanotechnology Excellence
3:50 p.m. - 4:10 p.m. Promises and Challenges in Image-Guided Cancer Therapy Using Theranostic Nanoparticles
Lily Yang
Emory University
Cancer Nanotechnology Platform Partnerships
4:10 p.m. - 4:30 p.m. Nanoscale Metal-Organic Frameworks for Imaging and Therapy of Pancreatic Cancer
Wenbin Lin
University of Chicago
Cancer Nanotechnology Platform Partnerships
4:30 p.m. - 4:50 p.m. Multicolor Quantum Dot Tracking for Studying Dynamic Protein Interactions
Janet Oliver
University of New Mexico
Cancer Nanotechnology Training Center
4:50 p.m. - 5:10 p.m. Sub-100 nm Gold Nanostructures for Cancer Theranostics
Amit Joshi
Baylor College of Medicine
Cancer Nanotechnology Platform Partnerships
5:10 p.m. - 5:30 p.m. RNA Nanotechnology in Cancer Therapy
Peixuan Guo
University of Kentucky
Cancer Nanotechnology Platform Partnerships

Wednesday, September 18

Session IV Translational Nanotechnologies at Spin-off Companies (8:30 a.m. - 10:30 a.m.)
Chair:
Zishan Haroon, The University of North Carolina, Chapel Hill

8:30 a.m. - 8:50 a.m. High Sensitivity Whole Blood Diagnostics With T2MR
Tom Lowery
Vice President, Diagnostics Research & Development
T2 Biosystems
9:10 a.m. - 9:30 a.m.

MagArray – Multiplex Diagnostic Platform for Protein Detection
Luis Carbonell
Chief Executive Officer
MagArray, Inc.

9:30 a.m. - 9:50 a.m. Aurasense - Spherical Nucleic Acid Nanoflares for Live Cell Detection of mRNA
David Giljohann
Principal Scientist, Chief Operating Officer
AuraSense Therapeutics, LLC
9:50 a.m. - 10:10 a.m. Sofie Biosciences - Accelerating PET Probe Discovery and Development
Patrick Phelps
President and Chief Executive Officer
Sofie Biosciences
10:10 a.m. - 10:30 a.m. CRLX101, a Topoisomerase-1 and HIF-1• Dual Inhitibor, in Phase 2 Clinical Trials in Advanced Solid Tumor Malignancies
Scott Eliasof
Vice President, Research
Cerulean Pharma Inc.
10:30 a.m. - 10:50 a.m. Break
Session V - Cancer Nanotechnology - Clinician's Perspective (10:50 a.m. - 12:30 p.m.)
Chair: Cheryl Willman, M.D., University of New Mexico Cancer Center

Nanotechnology in Breast and Blood Cancers
Steve Rosen, Northwestern University

Pancreatic Cancer
Steven Libutti, Albert Einstein College of Medicine

Ovarian Cancer
Anil Sood, University of Texas MD Anderson Cancer Center

Lung Cancer – Intra-operative Imaging
Sunil Singhal, University of Pennsylvania

Nanotechnology and Radiation Therapy
Joel Tepper, The University of North Carolina at Chapel Hill

12:30 p.m. - 2:00 p.m. Lunch (on your own)
2:00 p.m. - 3:00 p.m. Translation and Commercialization Panel
Chair: Mostafa Analoui, Livingston Group

Mostafa Analoui
Head of Healthcare and Life Sciences
Livingston Securities

Vahe Bedian
Director, Oncology Strategy, Licensing
Astra Zeneca

Peter Brown
Head of Oncology Therapeutic Area
Teva Pharmaceuticals

3:00 p.m. - 3:10 p.m. Break

Session VI-A (Parallel Sessions, 3:10 p.m. - 5:10 p.m.)
Chair: Lily Yang, Emory University

3:10 p.m. - 3:30 p.m.

Photonic Gene Circuits and iMDx for Cancers
Luke Lee
UC Berkeley
Center of Cancer Nanotechnology Excellence

3:30 p.m. - 3:45 p.m. Near Infrared Fluorescent Polysaccharide-Based Nanoparticles for Image-Guided Tumor Surgery
Aaron Mohs
Wake Forest - Virginia Tech School of Biomedical Engineering and Sciences
Path to Independence Award
3:45 p.m. - 4:00 p.m. Nanomedicines for the Management of Breast Cancer
Prakash Rai
University of Massachusetts, Lowell
Path to Independence Award
4:00 p.m. - 4:15 p.m. Dual Functions of Salinomycin in a Drug Delivery System Targeting Cancer Stem Cells
Mingnan Chen
University of Utah
Path to Independence Award
4:15 p.m. - 4:30 p.m. Near-Infrared Persistent Luminescent Nanoprobes for Ultrasensitive Bio-Imaging
Jin Xie
University of Georgia
Path to Independence Award
4:30 p.m. - 4:50 p.m. Sensing With Magnetic Nanoparticles
John Weaver
Dartmouth College
Center of Cancer Nanotechnology Excellence
4:50 p.m. - 5:10 p.m. Midwest Cancer Nanotechnology Training Center at University of Illinois at Urbana-Champaign
Rashid Bashir
University of Illinois at Urbana-Champaign
Cancer Nanotechnology Training Center

Session VI-B (Parallel Sessions, 3:10 p.m. - 4:55 p.m.)
Chair: Marc Porter, University of Utah

3:10 p.m. - 3:30 p.m. UCSD Cancer Nanotechnology Training Center
Andrew Kummel
University of California, San Diego
Cancer Nanotechnology Training Center
3:30 p.m. - 3:45 p.m. Next-Generation Quantum Dots for Molecular and Cellular Imaging of Cancer
Andrew Smith
University of Illinois at Urbana-Champaign
Path to Independence Award
3:45 p.m. - 4:00 p.m. Tumor Targeting and Diagnostic Applications of Glycosylated Nanotubes
Ravi Singh
Wake Forest University School of Medicine
Path to Independence Award
4:00 p.m. - 4:15 p.m. Biomarker-Responsive Ultrasound Contrast Agents Through Tuning of Interfacial Properties
Andrew Goodwin
University of Colorado, Boulder
Path to Independence Award
4:15 p.m. - 4:35 p.m. Reexamining the Size/Charge Paradigm: Differing In Vivo Characteristics of Size and Charge-Matched Mesoporous Silica Nanoparticles
C. Jeffrey Brinker
University of New Mexico
Cancer Nanotechnology Platform Partnerships
4:35 p.m. - 4:55 p.m. Training and Research Outcomes From Co-Mentored, Cross-Disciplinary Networks
Bennett Goldberg
Boston University
Cancer Nanotechnology Training Center
5:00 p.m. Poster Session
**Poster presenters are asked to stand by their posters from 5:30 p.m. to 6:00 p.m.

Thursday, September 19

Session VII (8:30 a.m. -  12:00 p.m.)
Chair: Chad Mirkin, Northwestern University

8:30 a.m. - 9:00 a.m. Novel Nanobiotechnology Approaches to Enhance Cancer Therapy
Joseph DeSimone
The University of North Carolina at Chapel Hill
Center of Cancer Nanotechnology Excellence
9:00 a.m. - 9:30 a.m. Nanobioconjugates for Imaging and Treatment of Primary and Metastatic Brain Cancer Using Tumor-Type Specific Biomarkers
Julia Ljubimova
Cedars-Sinai Medical Center
Cancer Nanotechnology Platform Partnerships
9:30 a.m. - 10:00 a.m. Combined Targeted Micellar Preparations of Novel Proapoptotic Drug and siRNAs for Cancer
Vladimir Torchilin
Northeastern University
Center of Cancer Nanotechnology Excellence
10:00 a.m. - 10:20 a.m. Break
10:20 a.m. - 10:30 a.m. Poster Student Awards
10:30 a.m. - 11:00 a.m. Local Hyperthermia Treatment of Primary Tumors Induces Antitumor Immune Responses
Steve Fiering
Dartmouth College
Center of Cancer Nanotechnology Excellence
11:00 a.m. - 11:30 a.m. A Very High-Capacity Polymeric Micelle Drug Delivery System
Alexander Kabanov
The University of North Carolina at Chapel Hill
Cancer Nanotechnology Platform Partnerships
11:30 a.m. - 12:00 p.m. Spherical Nucleic Acids (SNAs) for the Treatment of Glioblastoma
Chad Mirkin
Northwestern University
Center of Cancer Nanotechnology Excellence
12:00 p.m. - 12:20 p.m. Summary and Closing Comments
Piotr Grodzinski
National Cancer Institute, NIH
Meeting Adjourns

 



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2013 Annual Principal Investigators Meeting - NCI Alliance for Nanotechnology in Cancer - September 17-19, 2013 - Bethesda, MD

National Cancer Institute U.S. Department of Health & Human Services National Institutes of Health USA.gov