The Cancer Genome Atlas' 4th Annual Scientific Symposium

The Cancer Genome Atlas' 4th Scientific Symposium
May 11-12, 2015
Natcher Conference Center
National Institutes of Health
Bethesda, MD


The TCGA Symposium will begin on Monday, May 11th at 9:00am and will conclude Tuesday, May 12th by 6:00pm.

Monday, May 11

8:00 a.m. – 9:00 a.m. Registration Natcher Auditorium Foyer
9:00 a.m. - 9:10 a.m.  Opening Remarks Natcher Auditorium
9:10 a.m. - 9:30 a.m. State of TCGA
Jean C. Zenklusen, Ph.D.
National Cancer Institute, NIH

Carolyn Hutter, Ph.D.
National Human Genome Research Institute, NIH

9:30 a.m. - 10:05 a.m. Keynote Address: Machines that Construct Cancer Pathways by Reading the Primary Literature
Paul Cohen, Ph.D., M.A.
Defense Advanced Research Projects Agency
10:05 a.m. - 11:30 a.m. Session I
10:05 a.m. - 10:30 a.m. Comprehensive Molecular Characterization of Papillary Renal Cell Carcinoma
W. Marston Linehan, M.D.
National Cancer Institute, NIH
10:30 a.m. - 10:50 a.m. High-Throughput Somatic Variant Impact Phenotyping Using Gene Expression Signatures
Angela N. Brooks, Ph.D.
Dana-Farber Cancer Institute
Broad Institute
10:50 a.m. - 11:10 a.m. CoMEt: A Statistical Approach to Identify Combinations of Mutually Exclusive Alterations in Cancer
Hsin-Ta Wu, M.S.
Brown University
11:10 a.m. - 11:30 a.m. Decoding Breast Cancer with Quantitative Radiomics & Radiogenomics:  Imaging Phenotypes in Breast Cancer Risk Assessment, Diagnosis, Prognosis, and Response to Therapy
Maryellen Giger, Ph.D.
University of Chicago
11:30 a.m. - 1:00 p.m. Lunch (on your own)
1:00 p.m. - 2:00 p.m.  Poster Viewing (Even Numbers) Natcher Atrium
2:00 p.m. - 3:25 p.m.  Session II Natcher Auditorium
2:00 p.m. - 2:25 p.m. Integrated Genomic Characterization of Pheochromocytoma and Paraganglioma
Matthew D. Wilkerson, Ph.D.
The University of North Carolina at Chapel Hill
2:25 p.m. - 2:45 p.m. A Multi-Cancer Gene Signature Associated with Stromal Activation
Sandra Orsulic, Ph.D.
Cedars-Sinai Medical Center
2:45 p.m. - 3:05 p.m. Integrated Analysis of TCGA Identifies Targets and Patient Populations for Antibody-Drug Conjugates
Wenyan Zhong, Ph.D.
3:05 p.m. - 3:25 p.m. Mutation Hotspots Associate with Gene Expression, Signaling Pathways, Protein Domains and Drug Response
Theo Knijnenburg, Ph.D.
Institute for Systems Biology
3:30 p.m. - 4:00 p.m. Break/Workshop Setup
4:00 p.m. - 6:00 p.m. Workshops I (1 hour, repeat second hour)
  Session 1: cBio Portal for Cancer Genomics
Nikolaus Schultz, Ph.D.
Memorial Sloan-Kettering Cancer Center
Balcony B
  Session 2: Writing an Approvable dbGaP Controlled  Data Access Request
Vivian Ota-Wang, Ph.D.
National Human Genome Research Institute, NIH

Brandon Floyd
National Human Genome Research Institute, NIH

Balcony C
  Session 3: TCGA Imaging Resources (Joint Workshop)
Fred Prior, Ph.D.
Washington University in St Louis

Lee Cooper, Ph.D.
Emory University

Dave Gutman, M.D., Ph.D.
Emory University

Justin Kirby
Frederick National Laboratory for Cancer Research

Natcher Auditorium
6:00 p.m.   Adjourn Day 1

Tuesday, May 12

8:00 a.m. - 9:00 a.m. Registration Natcher Auditorium Foyer
9:00 a.m. - 10:25 a.m. Session III Natcher Auditorium
9:00 a.m. - 9:25 a.m. Integrated Molecular Characterization of Uterine Carcinosarcoma
Rehan Akbani, Ph.D.
The University of Texas MD Anderson Cancer Center
9:25 a.m. - 9:45 a.m. Characterization of Tumor-infiltrating T-lymphocytes in TCGA Cancers
Linghua Wang, Ph.D.
Baylor College of Medicine
9:45 a.m. - 10:05 a.m. Global Analysis of Somatic Structural Alterations and Their Impact on Gene Expression in Diverse Human Cancers
Babak Alaeimahabadi, M.S.
University of Gothenburg
10:05 a.m. - 10:25 a.m. Radiogenomic Analysis of TCGA/TCIA Diffuse Lower Grade Gliomas by Molecular Subtype
Laila M. Poisson, Ph.D.
Henry Ford Health System
10:25 a.m. - 10:45 a.m. Break
10:45 a.m. - 12:10 p.m. Session IV
10:45 a.m. - 11:10 a.m. Integrative Molecular Analysis Across Adult Glioma Reveals Novel Relationships Between Histological Subtypes And Molecular Signatures
Houtan Noushmehr
University of Sao Paulo
11:10 a.m. - 11:30 a.m. The Landscape of Somatic Structural Rearrangements in RAS Pathway Genes
Angeliki Pantazi, M.D., Ph.D.
Harvard Medical School
11:30 a.m. - 11:50 a.m. Somatic Copy Number Alterations and Aneuploidy Events in Uveal Melanoma
Juliann Shih
Broad Institute
11:50 a.m. - 12:10 p.m. The Landscape of Driver Kinase Fusions in Cancer
Nicolas Stransky, Ph.D.
Blueprint Medicines
12:10 p.m. - 1:30 p.m. Lunch (on your own)
1:30 p.m. - 2:30 p.m. Poster Viewing (Odd Numbers) Natcher Atrium
2:30 p.m. - 3:35 p.m. Session V
2:30 p.m. - 2:55 p.m. Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma
Tom Giordano, M.D. Ph.D.
University of Michigan
2:55 p.m. - 3:15 p.m. NCI Cloud Pilots Report
Tanja Davidsen, Ph.D.
National Cancer Institute, NIH
3:15 p.m. - 3:35 p.m. Analysis of Paired Tumor and Normal Data in TCGA
Andrew M. Gross
University of California, San Diego
3:35 p.m. - 4:00 p.m. Break/Workshop Set-up
4:00 p.m. - 6:00 p.m.   Workshops II (1 hour, repeat second hour)
  Session 1: FireBrowse: Mining the Firehose of TCGA
Mike Noble, M.S.
Broad Institute
Balcony B
  Session 2: Social Media for Scientists
Emma J. Spaulding, M.P.H.
National Cancer Institute, NIH
Balcony C
  Session 3: NCI Cancer Genomics Cloud Pilots
Gad Getz, Ph.D., M.S.
Broad Institute

Deniz Kural, Ph.D.
Seven Bridges Genomics

Ilya Shmulevich, Ph.D.
Institute for Systems Biology

Natcher Auditorium
6:00 p.m. Adjourn Day 2
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The Cancer Genome Atlas' 4th Scientific Symposium