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| Tuesday, October 24, 2006 |
| 5:00 p.m. - 8:00 p.m. |
Registration - Salons E-H, La Jolla Ballroom Foyer
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| 6:00 p.m. - 8:00 p.m. |
Commercialization Forum - Salons F-H, La Jolla Ballroom
Session Chair:
Sadik C. Esener, Ph.D.
University of California, San Diego
Invited Speakers:
Patrick Soon-Shiong, M.D.
Chairman of the Board and Chief Executive Officer
Abraxis BioScience, Inc.
Andrew "Drew" E. Senyei, M.D.
General Partner and Managing Director
Enterprise Partners Venture Capital
Claude D. Benchimol, Ph.D.
Senior Vice President of Research and Development
Invitrogen Corporation
David R. Parkinson, M.D.
Senior Vice President, Oncology Research and Development
Biogen Idec
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| Wednesday, October 25, 2006 |
| 7:00 a.m. - 6:30 p.m. |
Registration - Salons E-H, La Jolla Ballroom Foyer
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| 7:00 a.m. - 8:00 a.m. |
Breakfast - Salons E-H, La Jolla Ballroom Foyer
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| 8:00 a.m. - 8:30 a.m. |
Opening Remarks - Salons E-H, La Jolla Ballroom
Anna D. Barker, Ph.D.
Deputy Director, Advanced Technologies and Strategic Partnerships
National Cancer Institute, NIH
Sadik C. Esener, Ph.D.
University of California, San Diego
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| 8:30 a.m. - 9:00 a.m. |
Plenary Presentation - Salons E-H, La Jolla Ballroom
Clinical Promise of Nanomedicine: Delivery and Penetration of Pathways Into Solid Tumors
Jan E. Schnitzer, M.D.
Scientific Director
Sidney Kimmel Cancer Center
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| 9:00 a.m. - 10:00 a.m. |
Session I: In Vivo Diagnostics and Imaging - Salons E-H, La Jolla Ballroom
Session Chair:
Sanjiv Sam Gambhir, M.D., Ph.D.
Stanford University
NCI Moderator:
Jerry S.H. Lee, Ph.D.
National Cancer Institute, NIH
Speakers:
Improved Magnetofluorescent Nanoparticles for Cancer Detection
Lee Josephson, Ph.D.
Harvard Medical School and
Massachusetts General Hospital
In Vivo Imaging With Quantum Dots
Jianghong Rao, Ph.D.
Stanford University
PET Imaging and Use of Microfluidics for Rapid Synthesis of Radiolabeled Molecular Imaging Probes
Michael E. Phelps, Ph.D.
University of California, Los Angeles
Bioactivated Nanoprobes for Molecular Imaging of Cancer
Thomas J. Meade, Ph.D.
Northwestern University
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| 10:00 a.m. - 10:30 a.m. |
Discussion - Salons E-H, La Jolla Ballroom
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| 10:30 a.m. - 10:45 a.m. |
Break
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| 10:45 a.m. - 11:15 a.m. |
Session I: In Vivo Diagnostics and Imaging (continued):
Research Enablers (Animal Model/Toxicology) - Salons E-H, La Jolla Ballroom
Speakers:
Intraperitoneally Administered Nanoporous Silicon Particles for the Treatment of Ovarian Cancer
Stephen B. Howell, M.D.
University of California, San Diego
Molecularly Tailored Mouse Models of Cancer for In Vivo Applications of Nanomedical Sciences
Alan Charest, Ph.D.
Massachusetts Institute of Technology
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| 11:15 a.m. - 11:45 a.m. |
Discussion - Salons E-H, La Jolla Ballroom
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| 11:45 a.m. - 2:00 p.m. |
Lunch - First Floor, Fountain Court
(Lunch will stop being served at 1:30 p.m.)
Poster Session I - First Floor, Newport and Irvine and Salons E-H Foyer
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| 12 noon - 1:00 p.m. |
Bioinformatics in Nanotechnology Working Group Luncheon - Third Floor, Santa Barbara Room
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| 2:00 p.m. - 2:30 p.m. |
Keynote Presentating - Salons E-H, La Jolla Ballroom
Thomas Kalil
Special Assistant to the Chancellor for Science and Technology
University of California, Berkeley
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| 2:30 p.m. - 3:45 p.m. |
Session II: Nanotherapeutics - Salons E-H, La Jolla Ballroom
Session Chair:
Gregory M. Lanza, M.D., Ph.D.
Washington University in Saint Louis
NCI Moderator:
Linda K. Molnar, Ph.D.
National Cancer Institute, NIH
Speakers:
Targeting Nanoparticles to the Tumor Endothelium
David A. Cheresh, Ph.D.
University of California, San Diego
Nanotechnology in Drug Delivery
James R. Baker, Jr., M.D.
University of Michigan
Photodestruction of Ovarian Cancer: ErbB3 Targeted Aptamer-Nanoparticle Conjugate
Tayyaba Hasan, Ph.D.
Harvard Medical School and
Massachusetts General Hospital
Nanoparticle Therapeutics: Examples and Outlook
Samuel A. Wickline, M.D.
Washington University in Saint Louis
How Can the NCI Nanotechnology Alliance Access the Drug Development Capabilities of the NCI?
Joseph Tomaszewski, Ph.D.
Deputy Director, Division of Cancer Treatment and Diagnosis
National Cancer Institute, NIH
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| 3:45 p.m. - 4:15 p.m. |
Discussion - Salons E-H, La Jolla Ballroom
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| 4:15 p.m. - 4:30 p.m. |
Break
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| 4:30 p.m. - 5:15 p.m. |
Session II: Nanotherapeutics (continued):
Research Enablers (Targeting Strategies) - Salons E-H, La Jolla Ballroom
Speakers:
Targeting Strategies: Engineered Antibodies and Proteins
Anna M. Wu, Ph.D.
University of California, Los Angeles
Ligand-Directed Perfluorocarbon Nanoparticles: The Issue of Targeting
Gregory M. Lanza, M.D., Ph.D.
Washington University in Saint Louis
Aptamers and Cancer Nanotechnology
Omid Farokhzad, M.D.
Brigham and Women's Hospital and Harvard Medical School
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| 5:15 p.m. - 5:45 p.m. |
Discussion - Salons E-H, La Jolla Ballroom
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| 6:30 p.m. - 10:00 p.m. |
Evening Event: Birch Aquarium at Scripps
2300 Expedition Way, La Jolla, California
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| 6:30 p.m. |
Buses depart for the Birch Aquarium at Scripps.
Hotel Lobby Buses run consistently from 6:30 p.m. - 10:00 p.m.
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| 6:30 p.m. - 7:15 p.m. |
Reception
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| 7:15 p.m. - 8:00 p.m. |
Dinner
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| 8:00 p.m. - 8:30 p.m. |
Keynote Presentation:
Evolution of Cancer Therapeutics
David R. Parkinson, M.D.
Senior Vice President, Oncology Research and Development
Biogen Idec
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| 10:00 p.m. |
Last bus leaves the Birch Aquarium at Scripps for the hotel.
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| Thursday, October 26, 2006 |
| 7:30 a.m. - 5:00 p.m. |
Registration - Salons E-H, La Jolla Ballroom Foyer
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| 7:30 a.m. - 8:25 a.m. |
Breakfast - Salons E-H, La Jolla Ballroom Foyer
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| 8:25 a.m. - 8:30 a.m. |
Morning Remarks - Salons E-H, La Jolla Ballroom
Piotr Grodzinski, Ph.D.
National Cancer Institute, NIH
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| 8:30 a.m. - 9:45 a.m. |
Session III: Nanomaterials in Biological Matrices - Salons E-H, La Jolla Ballroom
Session Chair:
Mauro Ferrari, Ph.D.
University of Texas Health Science Center, Houston
NCI Moderator:
Travis M. Earles
National Cancer Institute, NIH
Speakers:
"Mother Ships" for Nanodiagnostics and Nanotherapeutics
Michael J. Sailor, Ph.D.
University of California, San Diego
Bridging the Imaging Gap in Nanobiology With Three-Dimensional Electron Microscopy
Sriram Subramaniam, Ph.D.
National Cancer Institute, NIH
Multifunctional Nanoparticle Probes for In Vivo Cancer Imaging
Shuming Nie, Ph.D.
Georgia Institute of Technology and Emory University
Anti-Biobarrier Nanotechnologies
Mauro Ferrari, Ph.D.
University of Texas Health Science Center, Houston
Organic Delivery Vehicles for Probing and Treating Biological Systems: Adapting Fabrication Processes From the Electronics Industry for Use in Nanomedicine
Joseph M. DeSimone, Ph.D.
The University of North Carolina at Chapel Hill
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| 9:45 a.m. - 10:15 a.m. |
Discussion - Salons E-H, La Jolla Ballroom
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| 10:15 a.m. - 10:30 a.m. |
Break
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| 10:30 a.m. - 11:10 a.m. |
Panel: Clinical Pathways for Nanotechnology - Salons E-H, La Jolla Ballroom
Speakers:
Characterization of Nanomaterials Intended for Medical Applications
Scott E. McNeil, Ph.D.
Director, Nanotechnology Characterization Laboratory
SAIC-Frederick, Inc.
National Cancer Institute, NIH
Nanotechnology: Stimulating Innovation Through Collaboration With the U.S. Food and Drug Administration
Wendy R. Sanhai, Ph.D.
Senior Scientific Advisor, Office of the Commissioner
U.S. Food and Drug Administration
Medical Nanodevices - Regulatory Perspectives
Subhas G. Malghan, Ph.D.
Deputy Director
Center for Devices and Radiological Health
U.S. Food and Drug Administration
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| 11:10 a.m. - 11:30 a.m. |
Question and Answer Session - Salons E-H, La Jolla Ballroom
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| 11:30 a.m. - 12 noon |
Multidisciplinary Research Training and Team Development - Salons E-H, La Jolla Ballroom
NCI Moderator:
Travis M. Earles
National Cancer Institute, NIH
Speakers:
Sri Sridhar, Ph.D.
Northeastern University
Carolyn J. Anderson, Ph.D.
Washington University in Saint Louis
Joanne Mortimer, M.D.
University of California, San Diego
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| 11:30 a.m. - 1:45 p.m. |
Poster Session II - First Floor, Newport and Irvine and Salons E-H Foyer
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| 12 noon - 1:45 p.m. |
Lunch - First Floor, Fountain Court
(Lunch will stop being served at 1:30 p.m.)
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| 12:15 p.m. - 1:45 p.m. |
Coordinating and Governance Committee (CGC) Luncheon Meeting - Third Floor, San Francisco
(invitation only)
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| 1:45 p.m. - 2:45 p.m. |
Session IV: In Vitro Diagnostics - Salons E-H, La Jolla Ballroom
Session Chair:
James R. Heath, Ph.D.
California Institute of Technology
NCI Moderator:
Piotr Grodzinski, Ph.D.
National Cancer Institute, NIH
Speakers:
Integrated System for Cancer Biomarker Detection
Scott Manalis, Ph.D.
Massachusetts Institute of Technology
Simultaneous and Quantitative Detection of Multiple Biomarkers in Human Breast Cancers Using Semiconductor Multicolor Quantum Dots
Ruth M. O'Regan, M.D.
Emory University
Carbon Nanomaterials for Biological Applications
Hongjie Dai, Ph.D.
Stanford University
Deconstructing Directional Cell Motility in Cancer Metastasis Through Nanopatterning
Bartosz A. Grzybowski, Ph.D.
Northwestern University
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| 2:45 p.m. - 3:15 p.m. |
Discussion - Salons E-H, La Jolla Ballroom
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| 3:15 p.m. - 3:30 p.m. |
Break
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| 3:30 p.m. - 4:15 p.m. |
Session IV: In Vitro Diagnostics (continued):
Research Enablers (Capture Agents/Technology Scale-Up) - Salons E-H, La Jolla Ballroom
Speakers:
Molecular Profiling of Murine Models and Human Prostate Cancer for Pathway-Specific Biomarker Discovery
Thomas Graeber, Ph.D.
University of California, Los Angeles
Science and Regulatory Perspectives of Medical Devices Using Nanotechnology
Subhas G. Malghan, Ph.D.
Deputy Director
Center for Devices and Radiological Health
U.S. Food and Drug Administration
Commercialization of Life Sciences Technologies: An Experience
J. Michael Ramsey, Ph.D.
The University of North Carolina at Chapel Hill
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| 4:15 p.m. - 4:45 p.m. |
Discussion - Salons E-H, La Jolla Ballroom
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| 4:45 p.m. - 5:00 p.m. |
Closing Remarks - Salons E-H, La Jolla Ballroom
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| 5:00 p.m. |
Adjournment
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